Se sabe igualmente desde hace tiempo que, cuando se toman durante un periodo prolongado, pueden provocar hemorragias digestivas al perforar la pared del estomago y el intestino.
Fuente:
- Acta Orthop Scand. 1979 Apr;50(2):169-74. Indomethacin treatment in osteoarthritis of the hip joint. Does the treatment interfere with the natural course of the disease? R?nningen H, Langeland N. / Double-Blind Clinical Evaluation of the Relative Efficacy of Ibuprofen and Glucosamine in the Management of Osteoarthrosis of the Knee in Outpatients. Antonio Lopes Vaz, M.D. Current Medical Research and Opinion Vol.8, No. 3, 1982.



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